TRT Therapy Cheat Sheet: Everything You Need To Know

Testosterone Replacement Therapy (TRT)

Testosterone Replacement Therapy (TRT) is gaining popularity among those with low testosterone levels, promising benefits like increased energy and muscle mass. Before starting your first session in Farmington, CT, it's essential to understand what TRT therapy entails, its potential benefits and risks, and how to know if it's right for you.

Table of Contents

What is TRT Therapy?

Benefits of TRT Therapy

Types of TRT Therapy

How to Prepare for Your First TRT Therapy Session

Who Should Avoid TRT Therapy?

How to Maximize the Effects of TRT Therapy

Frequently Asked Questions (FAQs)


Key Takeaways

  • TRT therapy restores testosterone levels, alleviating symptoms like fatigue, low libido, and muscle weakness.
  • Various TRT methods exist, including injections, gels, patches, and pellets tailored to individual needs.
  • Consistent monitoring is essential during TRT therapy to ensure safety, efficacy, and optimal results.
  • TRT therapy may enhance muscle mass, bone density, mood, energy levels, and overall well-being.
  • TRT therapy isn't suitable for everyone, especially those with certain medical conditions like prostate cancer.
  • Good candidates for TRT therapy have consistently low testosterone levels, along with symptoms affecting daily life.
  • Careful consideration and discussion with a healthcare provider are vital before starting TRT therapy.

What is TRT Therapy?

TRT therapy is a medical treatment designed to boost or restore testosterone levels in individuals with low or declining testosterone. Testosterone is a crucial hormone responsible for various functions, including muscle growth, energy production, mood regulation, sexual drive, and bone density. 

Testosterone levels naturally decrease as men age, but some individuals experience more significant declines. This often leads to a condition known as hypogonadism.

TRT therapy aims to address the symptoms of low testosterone, such as fatigue, reduced libido, muscle loss, and mood swings. It can be administered in various forms, including injections, gels, patches, pellets, and oral tablets. The method and dosage are tailored to individual needs and medical history.

Benefits of TRT Therapy

TRT therapy can bring a range of positive effects to individuals with low testosterone. Here are the key benefits of TRT therapy, each with a closer look at how it can improve quality of life:

Improved Energy and Vitality

Low testosterone often leads to fatigue and reduced energy levels. TRT therapy can reverse this by restoring testosterone to normal levels. Individuals report feeling more energized and able to engage in daily activities without the constant sense of exhaustion.

Increased Muscle Mass and Strength

Testosterone plays a pivotal role in muscle growth and maintenance. TRT therapy can help those with low T regain muscle mass and strength. This is particularly useful for individuals who have noticed muscle loss over time, as TRT therapy supports muscle rebuilding and improved physical performance.

Enhanced Libido and Sexual Function

A decline in testosterone can impact libido and sexual function. TRT therapy can increase sexual desire and improve erectile function. This often leads to a better quality of life, especially for individuals who have experienced a significant reduction in their sex drive.

Improved Mood and Mental Health

Low testosterone can contribute to mood swings, irritability, and even depression. TRT therapy has been shown to stabilize mood, leading to a more positive outlook and reduced irritability. This can have a ripple effect on personal relationships and overall well-being.

Better Bone Density and Cardiovascular Health

Testosterone contributes to maintaining bone density, reducing the risk of osteoporosis. Through ongoing research exploring these links, TRT therapy can positively impact cardiovascular health. This can lead to a healthier life with reduced risk of bone fractures and cardiovascular issues. 

Testosterone replacement therapy has become increasingly popular in the United States in recent years due to its numerous benefits. Since 1993, there has been a staggering 500% increase in the sales of prescription testosterone products.

Types of TRT Therapy
Types of TRT Therapy

TRT therapy comes in various forms, each with its advantages and disadvantages. Here's an overview of the common types of TRT therapy:


Injectable testosterone is one of the most widely used and cost-effective forms of TRT. This method involves receiving testosterone shots, either under the skin or into the muscle. The frequency and dosage depend on whether you opt for short-acting or long-acting treatment.

    • Short-acting treatment: This typically involves an injection every 1-2 weeks, providing a consistent release of testosterone.
    • Long-acting treatment: The first shot is followed by a second after 4 weeks, and subsequent injections are 10 weeks apart. These injections are usually administered in the gluteal muscles.

Fluctuations in testosterone levels can occur with injectable TRT, affecting energy levels, libido, mood, and symptoms such as breast tenderness. This fluctuation is often a consideration when choosing this type of therapy.

Topical (Transdermal)

Topical TRT involves applying testosterone gels or creams to the skin, allowing gradual absorption for more stable hormone levels. Topical patches are also available, providing a steady release over 24 hours. 

Here's a closer look at each:

    • Gels and creams: Applied daily, these require careful handling to avoid skin-on-skin contact with others for at least 6 hours after application. This precaution is crucial to prevent unintended transfer, which can be dangerous for pregnant people and children.
    • Patches: These stick to the skin and are replaced every 24 hours. They typically come in doses ranging from 2 mg to 5 mg. While patches are less toxic to the liver than oral medications, they might cause skin irritation and are less cosmetically appealing.

Cheek or Buccal Patches

Buccal patches are placed above the upper teeth and release testosterone over 12 hours. This method requires applying the patch twice daily, around 12 hours apart. While convenient, buccal patches can cause headaches and irritation to the gums or mouth.

Testosterone Implants or Pellets

Implants involve small pellets inserted under the skin, typically in the upper hip or buttock. These pellets dissolve slowly, providing a consistent release of testosterone over 3-6 months. This method requires a minor surgical procedure for insertion under local anesthesia. The dosage varies, and discussing this with your doctor before implantation is essential.

Oral Testosterone

Oral testosterone is less common due to its potential risks, including liver damage and increased blood pressure. This form is typically reserved for individuals who cannot use other forms of TRT. The dosage ranges from 225-396 mg, with tablets taken twice daily. Due to its risks, oral testosterone is considered a last resort.


Intranasal testosterone involves applying a gel to the inside of the nose. This requires application three times daily, at 6-8 hour intervals, with a total dosage of 33 mg daily. This method is convenient for those who prefer avoiding injections or topical applications, but it requires precise timing and can cause nasal irritation.

How to Prepare for Your First TRT Therapy Session

Preparing for your first TRT therapy session involves several essential steps to ensure a smooth and successful experience.

1. Pre-Session Preparation

  • Consult Your Doctor: Consult your healthcare provider in Farmington, CT, to discuss your symptoms and treatment expectations. This is a time to address any pre-existing health conditions and medications that might influence your TRT plan.
  • Blood Tests: TRT should begin with a comprehensive blood test to assess your baseline testosterone levels and other relevant markers, such as lipid profile and liver function. Ensure these tests are completed a few days before your session so your doctor has the latest information.
  • Diet and Lifestyle: While TRT can significantly impact testosterone levels, combining it with a healthy lifestyle can enhance the benefits. Eat a balanced diet, exercise regularly, and avoid excessive alcohol consumption to optimize your results.

2. Day of the Session

  • What to Bring: Prepare a list of all medications you are currently taking, including over-the-counter drugs and supplements. Bring any recent blood test results and a notepad to jot down information during the session.
  • Dress Appropriately: If your treatment involves an area of your body like the buttocks or thigh, wear loose-fitting clothing to facilitate easy access for injections.
  • Mental Preparation: Approach your first session with a positive mindset. Understanding that TRT is a step towards improving your health can help mitigate any anxiety you may feel.

3. Post-Session Care

  • Follow Instructions: Your healthcare provider will give specific instructions regarding the administration of TRT and its management. Follow these guidelines closely to avoid complications and maximize the therapy's effectiveness.
  • Monitor Your Body: Pay attention to how your body reacts after the session. If you experience any unusual symptoms, report them to your doctor immediately.

Who is a Good Candidate for TRT Therapy?

TRT therapy is not suitable for everyone. To determine if you're a good candidate, consider the following factors:

Individuals with Consistently Low Testosterone Levels

A crucial criterion for TRT therapy is having consistently low testosterone levels, confirmed by blood tests. Levels can fluctuate throughout the day, so your healthcare provider will likely recommend multiple tests to ensure accuracy. A reading below 300 nanograms per deciliter (ng/dL) is typically considered low for adult men, but this threshold may vary.

Those Experiencing Symptoms of Low Testosterone

Low testosterone, also known as hypogonadism, can cause various symptoms, including fatigue, reduced libido, muscle loss, mood swings, and difficulty concentrating. Good candidates for TRT therapy often experience one or more of these symptoms, affecting their quality of life.

Candidates without Contraindications

A good candidate for TRT therapy should have no medical conditions that would contraindicate its use. This includes conditions like prostate cancer, severe sleep apnea, elevated hematocrit levels, or a history of cardiovascular issues. A thorough medical evaluation is essential to rule out any potential risks.

Individuals Committed to Regular Monitoring

TRT therapy requires ongoing monitoring to ensure effective treatment and manage side effects. Good candidates are willing to commit to regular follow-up appointments, blood tests, and physical exams. This monitoring helps track testosterone levels and detect any adverse effects early.

TRT Candidates Open to Lifestyle Changes

While TRT therapy is more commonly prescribed for older men experiencing age-related testosterone decline, younger individuals with hypogonadism can also be candidates. Additionally, lifestyle factors such as obesity, poor diet, and lack of exercise can contribute to low testosterone. Candidates willing to make positive lifestyle changes alongside TRT therapy often experience better results.

Who Should Avoid TRT Therapy?

The Endocrine Society has identified several conditions and risk factors that suggest individuals should avoid TRT therapy. Here's a detailed look at who should avoid TRT therapy and why:

Individuals with Obstructive Sleep Apnea

TRT can exacerbate severe obstructive sleep apnea (OSA). It can cause neuromuscular changes to the airways and chemical changes in metabolism, leading to reduced oxygen levels (hypoxia). Hypoxia can result in symptoms like confusion, restlessness, difficulty breathing, rapid heart rate, and bluish skin.

Additionally, TRT therapy can lead to hypercapnia, a condition where carbon dioxide levels become too high in the blood. Hypercapnia can cause respiratory acidosis, with symptoms such as fatigue, drowsiness, or a strong desire to sleep.

Patients with Elevated Hematocrit Levels and Thrombophilia

People with high red blood cell counts or thrombophilia should avoid TRT therapy. TRT therapy can increase red blood cell counts, leading to higher blood viscosity and a greater risk of blood clot formation, stroke, or ischemia. A 2021 study on trans men using long-term TRT therapy found an increase in red blood cell count of 10% after one year and 38% after ten years, indicating a potential risk for those with high hematocrit levels.

Those with Prostate Cancer

Prostate cancer relies on testosterone to grow. TRT therapy could stimulate the growth of prostate cancer cells, making it unsuitable for those with an existing diagnosis or a history of prostate cancer. According to the National Cancer Research Institute, men with higher levels of testosterone in their blood are more likely to be diagnosed with prostate cancer.

Individuals with Heart Conditions

TRT therapy can increase the risk of cardiovascular conditions, including ischemic stroke. A study of 15,401 men aged over 45 years with low testosterone levels found that those who received TRT therapy had a greater risk of cardiac arrest and cerebrovascular disease compared to those who did not take TRT therapy.

How to Choose the Best PRP Injections Provider for Hair Loss Treatment

Selecting the right provider for your PRP injections in Farmington, CT, is crucial for ensuring safe and effective treatment outcomes. Here are seven essential tips to help you choose the best PRP injection provider:

1. Research Qualifications and Experience

When choosing a PRP therapy provider, prioritize those with specialized training in PRP injections for hair loss, like BioRestore. Ensure they hold the necessary qualifications and certifications from recognized medical organizations. Look for providers who communicate the treatment process, risks, benefits, and expected outcomes and are readily available to address any concerns. Also, confirm their licensing and accreditation with relevant authorities to ensure safety and quality standards compliance.

2. Assess Reputation and Patient Reviews

Before committing to a PRP provider, take the time to assess their reputation and read patient reviews. Look for testimonials from individuals who have undergone PRP treatment with your chosen provider. Positive reviews and testimonials can provide valuable insights into the quality of care and satisfaction levels among previous patients.

3. Evaluate Facility and Equipment

Visit the facility where PRP injections are performed and assess the quality of the equipment and the environment. Ensure the facility adheres to strict hygiene and safety standards to minimize the risk of infection or complications during the procedure. State-of-the-art equipment and modern facilities are indicators of a reputable PRP provider.

4. Inquire About Treatment Plans and Protocols

Ask the provider about their treatment protocols and techniques for PRP injections. Inquire about their specific process, including blood collection, centrifugation, and injection procedures. A knowledgeable provider should be able to explain their approach in detail and address any concerns or questions you have about the treatment.

5. Discuss Cost and Payment Options

Discuss the cost of PRP injections and inquire about payment options with the provider. While cost should not be the sole determining factor, it's essential to understand the financial aspect of treatment upfront. Ask about any potential additional fees or charges and explore payment plans or financing options available to you.

How to Maximize the Effects of TRT Therapy

How to Maximize the Effects of TRT Therapy

TRT Therapy can help in many ways, but there are still practical steps you can take to get the most out of this treatment. Here are some tips to follow: 

1. Optimize Your Diet

Maintaining a balanced diet is crucial for supporting the effectiveness of TRT therapy. Focus on consuming foods rich in protein, healthy fats, and essential nutrients to provide your body with the building blocks for optimal hormone production. Lean meats, eggs, nuts, and leafy greens are excellent choices that can help boost testosterone levels. Avoiding processed foods, sugary snacks, and excessive alcohol consumption is also important, as these can negatively impact hormone balance and overall health.

2. Apply Strategic Exercise Routine

Regular exercise is a key component of maximizing the benefits of TRT therapy. Incorporate cardiovascular exercises and strength training into your routine to promote muscle growth and testosterone production. Aim for at least 150 minutes of moderate or 75 minutes of vigorous-intensity exercise per week. Focus on compound movements like squats, deadlifts, and bench presses, as these exercises are particularly effective for stimulating testosterone release and muscle development.

3. Manage Stress Effectively

Chronic stress can interfere with hormone balance and diminish the effectiveness of TRT therapy. Practice stress-reduction techniques such as deep breathing exercises, mindfulness meditation, or yoga to help calm your mind and reduce stress levels. Prioritize relaxation and self-care activities to create a healthy balance in your life. If stress becomes overwhelming, consider seeking support from a therapist or counselor to develop coping strategies and improve your overall well-being.

4. Practice Optimal Sleep Habits

Quality sleep is essential for hormone regulation and overall health, prioritizing optimal sleep habits for maximizing the effects of TRT therapy. Aim for 7-9 hours of quality sleep per night and establish a consistent sleep schedule to support your body's natural rhythms. Create a relaxing bedtime routine to signal to your body that it's time to wind down, and ensure your sleep environment is conducive to rest with a comfortable mattress, minimal noise, and dim lighting.

5. Avoid Interference

Be vigilant about potential interactions between TRT therapy and other medications or supplements. Some medicines and supplements may interfere with the effectiveness of TRT or pose risks when combined. Before starting new medications or supplements, consult your healthcare provider to minimize potential complications. Stay informed about possible interactions and promptly discuss any concerns with your provider to ensure the safety and effectiveness of your TRT therapy.

Frequently Asked Questions (FAQs)

Is TRT therapy safe?

TRT therapy is generally safe when prescribed and monitored by a qualified healthcare professional. However, like any medical treatment, it carries potential risks. Common side effects include acne, fluid retention, increased red blood cell counts, and mood swings. 

How long does TRT therapy take to work?

The effects of TRT therapy can vary depending on the individual and the type of TRT therapy used. Some people report noticeable improvements in energy and libido within a few weeks, while others take longer to see significant changes. The timeline for noticeable benefits can range from several weeks to a few months.

Can women undergo TRT therapy?

While TRT therapy is typically associated with men, women can also undergo TRT therapy in specific cases. Women with low testosterone levels can benefit from TRT therapy to address symptoms like fatigue, muscle loss, and reduced libido. However, the dosage and approach for women differ from those for men.

Will TRT therapy affect fertility?

TRT therapy can impact fertility, especially in men, by reducing sperm production. Testosterone is crucial for sperm production, and supplementing with TRT therapy can signal the body to reduce or stop its production. If fertility is a concern, it's important to discuss this with your healthcare provider before starting TRT therapy. Alternative treatments or methods to preserve fertility are recommended.

How much does TRT therapy cost?

The cost of TRT therapy can vary depending on several factors, including the type of treatment, duration of therapy, and healthcare provider fees. Generally, TRT therapy expenses may include the cost of medications (such as testosterone injections, gels, or patches), laboratory tests, doctor consultations, and follow-up appointments. Insurance coverage may also influence the out-of-pocket expenses for TRT therapy. 

Unlock the Power of TRT with BioRestore!

TRT therapy holds promise in alleviating symptoms of Low-T and improving overall quality of life for many individuals. If you're exploring TRT options in Farmington, CT, consider reaching out to BioRestore, a trusted provider of hormone therapy. With their expertise and personalized approach, BioRestore can help guide you through the process and tailor a treatment plan to suit your unique needs. Take the first step towards reclaiming your vitality and well-being – contact us today!